Spinach Artichoke Chicken Stuffed Pita

Featured in: Everyday Comfort Meals

This Mediterranean-inspired dish combines tender chicken breast with fresh spinach and artichoke hearts in a creamy yogurt-based filling. Pita breads are generously stuffed and baked until the cheese melts and the filling turns golden. Ready in just 40 minutes with minimal prep work, making it ideal for weeknight dinners or meal prep. The high-protein filling keeps you satisfied, while the combination of Greek yogurt and fresh herbs adds authentic Mediterranean flavor.

Updated on Tue, 20 Jan 2026 08:32:00 GMT
Golden-brown, lightly toasted pita pockets stuffed with creamy spinach, artichoke, and tender chicken, garnished with fresh parsley. Pin it
Golden-brown, lightly toasted pita pockets stuffed with creamy spinach, artichoke, and tender chicken, garnished with fresh parsley. | soupbuffer.com

The first time I made these stuffed pitas, my kitchen smelled like a Mediterranean restaurant had moved in. I was trying to use up leftover rotisserie chicken and a random can of artichokes, and somehow this combination ended up being the kind of dinner that makes people pause between bites.

My sister-in-law walked in mid-prep and literally asked if I was making spinach dip. When I explained it was actually dinner, she looked skeptical, but then ate two stuffed pitas straight off the baking sheet. Now she requests them every time she visits.

Ingredients

  • 2 cups cooked chicken breast: Rotisserie chicken works perfectly here and saves so much time, plus it adds that seasoned flavor
  • 1 cup canned artichoke hearts: Chop them pretty small so they distribute evenly throughout every bite
  • 1 cup fresh spinach: Fresh spinach wilts nicely in the oven, frozen would make the filling too watery
  • 1/2 cup Greek yogurt: This keeps the filling creamy without being too heavy like traditional cream cheese versions
  • 1/4 cup light mayonnaise: Just enough to bind everything together with that familiar spinach dip flavor
  • 1/2 cup shredded mozzarella cheese: The cheese that makes everything better and helps the filling stay put inside the pita
  • 1/4 cup grated Parmesan cheese: Adds that salty, nutty depth that makes spinach artichoke anything so addictive
  • 1 clove garlic: Minced fresh garlic is non-negotiable here, powder just does not compare
  • 1/2 teaspoon onion powder: Rounds out the savory notes without adding any crunch
  • 1/2 teaspoon dried oregano: Gives it that Mediterranean flair we all love
  • 1/4 teaspoon crushed red pepper flakes: Totally optional, but I love the subtle warmth it provides
  • Salt and black pepper: Taste your filling before stuffing the pitas to get the seasoning right
  • 4 large pita breads: Whole wheat adds a nice nutty flavor, but regular works perfectly too
  • Fresh parsley: A little pop of color and freshness on top makes these feel fancy
  • Lemon wedges: A squeeze of bright acid cuts through all that creamy richness beautifully

Instructions

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Preheat and prep:
Get your oven to 375°F and line a baking sheet with parchment paper for easier cleanup later.
Mix the filling:
Combine everything except the pitas and garnish in a large bowl until the chicken is evenly coated in that creamy, cheesy mixture.
Prep the pitas:
Cut each pita in half to make pockets, being careful not to tear all the way through.
Stuff generously:
Spoon that spinach artichoke chicken mixture into each pita half, really packing it in there.
Arrange and bake:
Lay the stuffed pitas on your prepared baking sheet and bake for 15 to 20 minutes until the cheese is melted and everything is hot throughout.
Finish and serve:
Let them cool for just a couple minutes, then hit them with fresh parsley and serve with lemon wedges on the side.
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Cook complete meals by frying, sautéing, simmering, and boiling with easy nonstick cleanup every day.
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Golden-brown baked pita halves filled with spinach artichoke chicken, melted mozzarella, and a hint of fresh lemon. Pin it
Golden-brown baked pita halves filled with spinach artichoke chicken, melted mozzarella, and a hint of fresh lemon. | soupbuffer.com

These have become my go-to when friends come over for casual dinners because everyone can customize their own, and they feel a little special without being fussy.

Make Ahead Magic

The filling can be mixed up to two days in advance and stored in the fridge. Just stuff and bake when you are ready to eat, which makes weeknight dinners feel much more manageable.

Perfect Pairings

A crisp green salad with a bright vinaigrette cuts through the richness perfectly. I also love serving these alongside roasted vegetables or a simple tomato cucumber salad for a complete Mediterranean-inspired meal.

Mix It Up

Sometimes I add sun-dried tomatoes or roasted red peppers to the filling for extra color and sweetness. You could also swap the chicken for cooked chickpeas to make a vegetarian version that is just as satisfying.

  • Try whole wheat pitas for extra fiber and a nuttier flavor
  • A little extra mozzarella on top never hurt anyone
  • These freeze beautifully before baking, just add a few extra minutes to the cook time
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A close-up of warm Spinach Artichoke Chicken Stuffed Pita, revealing the creamy filling and melted cheese inside. Pin it
A close-up of warm Spinach Artichoke Chicken Stuffed Pita, revealing the creamy filling and melted cheese inside. | soupbuffer.com

Hope these become a regular rotation in your kitchen like they have in mine.

Recipe FAQs

Can I use frozen spinach instead of fresh?

Yes, frozen spinach works well. Thaw and squeeze out excess moisture thoroughly before mixing into the filling to prevent the pita from becoming soggy.

What can I substitute for Greek yogurt?

Cream cheese, sour cream, or ricotta are excellent alternatives. Cream cheese will create a richer, denser filling, while sour cream offers similar tanginess to Greek yogurt.

How do I store and reheat leftovers?

Store stuffed pitas in an airtight container in the refrigerator for up to 3 days. Reheat in a 350°F oven for 10-12 minutes until warmed through, or microwave for 1-2 minutes per serving.

Can I make the filling ahead of time?

Absolutely. Prepare the filling up to 24 hours in advance and store it separately from the pita bread. Stuff and bake just before serving for the best texture and melted cheese.

What sides pair well with this dish?

A crisp green salad with lemon vinaigrette complements the rich filling perfectly. Roasted vegetables, hummus with pita chips, or a light soup are also great accompaniments.

Is this dish suitable for meal prep?

Yes, you can prepare the filling and store it separately for up to 3 days. Stuff and bake fresh when ready to eat, or bake ahead and reheat gently to maintain quality.

Spinach Artichoke Chicken Stuffed Pita

Fluffy pita pockets stuffed with a creamy blend of spinach, artichokes, chicken, and melted cheese. Easy Mediterranean comfort food.

Prep Time
20 minutes
Time to Cook
20 minutes
Overall Time
40 minutes
Created by Audrey Taylor


Skill Level Easy

Cuisine Type Mediterranean-American

Makes 4 Portions

Diet Preferences None specified

What You'll Need

Chicken & Filling

01 2 cups cooked chicken breast, diced or shredded
02 1 cup canned artichoke hearts, drained and chopped
03 1 cup fresh spinach, chopped
04 1/2 cup Greek yogurt
05 1/4 cup light mayonnaise
06 1/2 cup shredded mozzarella cheese
07 1/4 cup grated Parmesan cheese
08 1 clove garlic, minced
09 1/2 teaspoon onion powder
10 1/2 teaspoon dried oregano
11 1/4 teaspoon crushed red pepper flakes
12 Salt and black pepper to taste

Bread

01 4 large pita breads

Garnish

01 Fresh parsley, chopped
02 Lemon wedges

Steps

Step 01

Preheat Oven: Heat oven to 375°F

Step 02

Prepare Filling: In a large mixing bowl, combine chicken, artichoke hearts, spinach, Greek yogurt, mayonnaise, mozzarella, Parmesan, garlic, onion powder, oregano, red pepper flakes, salt, and black pepper. Mix until well combined.

Step 03

Prepare Pita Pockets: Slice pita breads in half to form pockets.

Step 04

Stuff Pitas: Generously fill each pita half with the spinach artichoke chicken mixture.

Step 05

Arrange for Baking: Place stuffed pitas on a baking sheet lined with parchment paper.

Step 06

Bake: Bake for 15 to 20 minutes until filling is hot and cheese is melted.

Step 07

Finish and Serve: Remove from oven and garnish with chopped parsley. Serve with lemon wedges.

Tools Needed

  • Mixing bowl
  • Spoon or spatula
  • Baking sheet
  • Knife
  • Parchment paper

Allergy Info

Review all components for allergens and talk to your health provider if unsure.
  • Contains dairy: yogurt and cheese
  • Contains eggs: mayonnaise
  • Contains wheat: pita bread
  • May contain soy depending on mayonnaise brand

Nutrition Details (per portion)

Details are for general guidance. Always seek expert healthcare advice.
  • Energy: 385
  • Fats: 13 g
  • Carbohydrates: 34 g
  • Proteins: 31 g